Welcome to The Wisconsin Medicago Group
Protein Compendium


For more details on the Medicago Protein Atlas please refer to the publication linked above.


When referencing this work in a paper or presentation please use the citation above.


This site hosts a number of tools for querying, visualizing, and making comparisons within the data.

About The Medicago Proteome

Legumes are essential components of agricultural systems because they enrich the soil in nitrogen and require little environmentally deleterious fertilizers. A complex symbiotic association between legumes and nitrogen-fixing soil bacteria called rhizobia culminates in the development of root nodules, where rhizobia fix atmospheric nitrogen and transfer it to their plant host. Here we describe a quantitative proteomic atlas of the model legume Medicago truncatula and its rhizobial symbiont Sinorhizobium meliloti, which includes more than 23,000 proteins, 20,000 phosphorylation sites, and 700 lysine acetylation sites. Our analysis provides insight into the symbiosis regulatory mechanism. We identify a calmodulin-binding protein as a key regulator in the host and assign putative roles and targets to host factors (bioactive peptides) that control gene expression in the symbiont. Further mining of this proteomic resource may enable engineering of crops and their microbial partners to increase agricultural productivity and sustainability.

Navigation Tools

All relevant information from the search results and data analysis were imported into a MySQL database. The results were supplemented by ordered gene locus identifiers and cross references to public databases (Ensembl, JCVI, UniProt, RefSeq). The interface to access the database was built with the Bootstrap front-end framework and data visualization implemented with the D3.js JavaScript library.

This page is best viewed with Google Chrome.